Penicillin injection in women is an injection of penicillin into a woman’s muscle. Intramuscular penicillin injections in women can be painful. Clinically, intramuscular injection of penicillin is painful. This is due to the fact that penicillin injection contains more sodium and potassium ions, which will cause pain when pushing the injection by producing obvious stimulation to the local skin and muscle tissues. Therefore, many women experience pain during intramuscular injections of penicillin. The degree of pain varies from person to person; some women with a high tolerance for pain have mild pain; women with a high sensitivity to painful stimuli will feel particularly painful during penicillin injections. Adverse reactions to penicillin include allergy, urticaria, leukopenia, interstitial nephritis, and asthma attacks, etc. Note that before performing penicillin therapy, a skin test must be performed to prevent the occurrence of adverse effects of the medication. In addition, when injecting penicillin intramuscularly, it is recommended to relax the muscles and eliminate the psychological tension, which can effectively reduce the pain. After intramuscular injection of penicillin, local hot compresses can be applied to promote blood circulation to relieve the pain level. For the use of drugs, you should actively tell the doctor whether there is any allergic reaction to such drugs in the past, so as to facilitate the doctor according to the individual situation of targeted and rational drug treatment. The drug needs to be used under the guidance of the doctor, do not blindly use the drug on your own, so as not to cause adverse consequences.