Sudden discontinuation of methotrexate is not recommended.
Methotrexate is a kind of antifolate antitumor drug, which can effectively inhibit the reproduction and growth of tumor cells, and also has a good therapeutic effect on rheumatoid arthritis. After methotrexate is suddenly stopped, although it will not cause obvious adverse reactions to the body, it will affect the therapeutic effect of the drug, delay the recovery of the condition, and even cause a relapse of the condition.
Methotrexate has more side effects, the common adverse reactions are gastrointestinal reactions, liver and kidney function damage and bone marrow suppression, etc. When taking this drug, you must use the drug under the guidance of a doctor, strictly according to the dosage prescribed by the doctor, and at the same time, you should monitor the liver and kidney function on a regular basis.