There is no fastest treatment for numbness of the thumb, clinically according to the cause of the treatment, such as cervical spondylosis given manipulation, traction therapy, etc.; diabetic peripheral neuropathy, the use of hypoglycemic drugs to adjust blood sugar (acarbose, etc.); Raynaud’s phenomenon use of vasodilating drugs (prostaglandin, etc.). 1. Cervical spondylosis. This disease is caused by the compression of the nerve roots in the neck. After the onset of the disease, oral methylcobalamin, adenosylcobalamin and other drugs are used to nourish the nerves. Traction therapy, manipulation therapy, acupuncture and so on improve the symptoms. 2. Diabetic peripheral neuropathy. This disease is mainly due to poor glycemic control, peripheral nerve involvement. After the onset of the disease, use hypoglycemic drugs, such as acarbose, glimepiride and other drugs to adjust the blood sugar; vitamin B1, vitamin B12 nutrition of the nerves and so on. 3. Raynaud’s phenomenon. This disease is caused by terminal vascular reasons. At the onset of the disease, vasodilating drugs can be used to improve circulation, such as prostaglandin, guipizide and so on. Numbness of the thumb should go to the hospital outpatient clinic as soon as possible and be treated under the guidance of the doctor.