Newborns with yellow watery eyes may be due to acute conjunctivitis, nasolacrimal duct, gonoconjunctivitis, etc. It is recommended to go to the hospital to find out the cause of the disease, according to the cause of the targeted treatment. 1. Acute conjunctivitis: may be because the newborn infected with bacteria or pathogens leading to eye infections, resulting in the newborn’s eyes yellow water, and manifested as conjunctival congestion is very obvious, it is recommended that you can use drugs for treatment, such as tobramycin eye drops, gatifloxacin eye drops, erythromycin ointment, and so on. 2. Nasolacrimal duct failure: may be because of the newborn’s nasolacrimal duct failure, the tears in the eye socket can not effectively flow into the nasal cavity, which leads to the blockage of the tears caused by bacterial infections, resulting in the phenomenon of yellowish water in the eyes. It can be treated by medication, such as chloramphenicol eye drops, diclofenac sodium eye drops, levofloxacin eye drops and so on. 3. Gonococcal conjunctivitis: mainly for pregnant women infected during the birth canal, after the birth of the newborn’s eyes and face will appear edema and congestion, the eyes appear a large number of pus secretions are yellow. It is recommended that treatment can be carried out by drugs, such as amoxicillin clavulanate potassium granules and so on. It is recommended to consult the doctor as soon as possible to clarify the diagnosis and then carry out targeted treatment. It is recommended that the above medication be used in accordance with medical advice to avoid adverse reactions and effects.