There are usually many patients with chronic renal failure in the clinic, many patients do not know the meaning of these symptoms, now the symptoms of chronic renal failure are summarized as follows: 1, chronic renal failure of the digestive system symptoms: common symptoms are dullness, nausea, vomiting, diarrhea and gastrointestinal bleeding and other manifestations. Gastrointestinal symptoms are the early clinical manifestations of chronic renal failure, which become increasingly prominent with the development of the disease and can become very serious at a later stage, often becoming one of the important complaints when patients visit the clinic. If patients with these symptoms should seek medical attention in a timely manner, the consultation can be done directly with me by phone to give you a timely treatment advice. 2, chronic renal failure of the cardiovascular system symptoms: cardiovascular system damage in uremic patients is very common, is one of the important causes of death in patients with chronic renal failure. Mainly including pericarditis, myocardial lesions, endocardial lesions, heart failure and hypertension, etc. Cardiac insufficiency is the main cause of death in patients with chronic renal failure. 3, chronic renal failure respiratory symptoms: the primary problem is lung infection. Pulmonary infection is one of the main causes of death in patients with chronic renal failure. Lung infections mainly include pneumonia, bronchopneumonia, bronchiectasis, 60% to 70% of which are Gram-negative bacillary infections, which can develop into serious infections if not treated in time. In addition, viral, fungal, and tuberculosis infections can also be seen. Next, it is often complicated by uremic lung and uremic pleurisy. So the early treatment of chronic renal failure correct treatment is particularly important, we should choose the regular hospital treatment, to the big hospital is not convenient can also be in advance and I telephone consultation to confirm the treatment method and timing. 4, chronic renal failure of the hematopoietic system symptoms: anemia is one of the important clinical manifestations of chronic renal failure patients, clinical symptoms are lighter than other kinds of chronic anemia, the tolerance of anemia is much stronger than normal people. Although the anemia is more severe, there are mostly no obvious palpitations, shortness of breath, chest tightness, accelerated heart rate and other manifestations. Patients often have significant bleeding tendency and bleeding manifestations. Patients with chronic renal failure are prone to infection due to impaired granulocyte and lymphocyte function, which becomes the main cause of death in acute and chronic renal failure. 5, chronic renal failure can lead to renal bone disease: most of them are divided into three types: high-running type, low-running type and mixed type. Clinically, bone pain, fracture and bone deformation are the main symptoms, and there can also be muscle and joint symptoms, muscle atrophy, periarthritis and aseptic necrosis of the femoral head. 6, chronic renal failure of the nervous system and muscular system symptoms: mainly fatigue, weakness, head weight, memory loss, often have difficulty concentrating, irritability and self-consciousness, calculating power and work efficiency decreased, insomnia and dreaminess and sleep pattern change, with the progress of chronic renal failure, the condition gradually aggravated, there may be emotional and personality changes, appear orientation, calculating power disorder and mental confusion, also can There can be mood and personality changes, disorientation, calculation disorders, mental confusion, and visual and auditory hallucinations. In the late stage, there is drowsiness, indifference, incontinence, and gradually coma. Muscle lesions are mainly characterized by muscle weakness, painful muscle spasms, muscle tremors, muscle atrophy, and erratic rebellion. 7. Endocrine function symptoms caused by chronic renal failure: insufficient secretion of hormones produced by the kidney, such as decreased erythropoietin production leading to renal anemia, 1,25(OH)2D3 deficiency leading to renal bone disease; reduced ability of the kidney to degrade and clear some hormones in the body; uremia can cause target tissue resistance to certain hormone effects, such as insulin due to impaired renal clearance, prolonged half-life and increased plasma levels However, the patient still shows typical glucose intolerance, which is mainly due to impaired insulin target tissue response. 8. Chronic renal failure leads to thyroid and gonadal dysfunction: symptoms such as fatigue, cold, drowsiness, slow thinking, false swelling, dry skin, and hypoactive nerve reflexes are often seen. Women show changes in menstrual cycle or menopause, reduced menstrual volume, decreased fertility, infertility and increased miscarriage and premature birth. 9, chronic renal failure leads to abnormal lipid metabolism: abnormal lipid metabolism in patients with chronic renal failure is mainly seen in triglycerides (TG), very low density lipoprotein (VLDL), low density lipoprotein (LDL) and apolipoprotein C II (apo-C II), apolipoprotein C III (apo-C III) significantly elevated, especially VLDL is particularly elevated. 10. Chronic renal failure leads to water-electrolyte disorders: in the early stage of chronic renal failure, polyuria or nocturia occurs, and oliguria or anuria is a serious late manifestation. Water metabolism disorder is manifested as water excess or water loss. Edema, heart failure and hypertension appear when sodium load is increased. Excessive restriction of sodium intake tends to lead to hyponatremia. Late oliguria and increased blood sodium can lead to acute hypernatremia if accompanied by high sodium food intake or excessive sodium bicarbonate input. Blood potassium is often elevated in the late stages of chronic renal failure. Hypokalemia is rare in chronic renal failure. Hypocalcemia and hyperphosphatemia are common in chronic renal failure. 11, chronic renal failure leads to acid-base imbalance imbalance: mainly metabolic acidosis. In the early stage, there are fatigue and weakness, anorexia, nausea, deepening of respiration, etc.; in severe cases, it is manifested as deep breathing, confusion, and even myocardial contraction weakness, abnormal conduction and death. The symptoms of chronic renal failure involve all aspects, the discovery of adverse symptoms we should seek medical attention in a timely manner, and to the regular large hospitals, timely treatment and correct treatment, the inconvenience of consultation can be done by telephone consultation and I communicate directly, so that before the consultation have a good idea.