TRAb is thyrotropin receptor antibody, also known as membrane receptor antibody, is an antibody that acts directly on the TSH receptor on the membrane of thyroid cells, and is an immunoglobulin IgG.
TRAb is a kind of thyroid autoantibody, mainly used for the diagnosis and differential diagnosis of Graves’ hyperthyroidism. If there are typical symptoms of hyperthyroidism, thyroid function is thyrotoxic manifestation, and TRAb is positive, then basically it can be diagnosed as Graves’ hyperthyroidism; if it is negative, then consider other causes of hyperthyroidism; if the diagnosis still can not be confirmed by using TRAb, then carry out the iodine uptake rate examination.
Thyrotropin receptor antibodies can be categorized into three types according to their functions: thyroid-stimulating antibodies (also known as thyroid-stimulating immunoglobulins), thyroid-suppressing antibodies (also known as thyroid-suppressing immunoglobulins), and thyroid-growth-stimulating immunoglobulins, and thyrotropin receptor antibodies on the high side and on the low side are all abnormal.
TRAb abnormalities should be treated under the supervision of a physician.