The choice of cephalosporin or levofloxacin for bronchitis is related to the patient’s condition, pathogen susceptibility and other factors. 1. Cephalosporin and levofloxacin are both antibiotics that can fight bacterial infection and control inflammation. In general, they can be used to treat acute bronchitis, but if you are allergic to cephalosporin, you should choose levofloxacin, and you need to do an allergy test before using cephalosporins to avoid allergic reactions. 2. The two mechanisms of action and antibacterial spectrum are slightly different. Levofloxacin mainly acts on the nucleus of bacterial cells and kills bacteria by inhibiting DNA replication, while cephalosporin acts on the bacterial cell wall and lyses the cells. The antibacterial spectrum of the two is different, levofloxacin has antibacterial effect on bacteria, mycoplasma, chlamydia, etc., while cephalosporin is only effective on bacteria. It is recommended that patients seek medical attention, under the guidance of the doctor reasonable choice of drugs to treat the disease.