For patients with SLE, especially lupus nephritis, how to have a smooth pregnancy and safe delivery, to be a happy mother and to add to a happy family has always been the expectation of the patients and one of the topics valued by the rheumatology community. It is difficult to elaborate on its details and details. 1. Patients with lupus nephritis are perfectly capable of conceiving normally (which can be interpreted as normal fertility). However, the main problem is how to keep the fetus developing and the mother and child safe after pregnancy. Even if the pathological type of kidney puncture is not good (such as type 3, type 4, etc.), after reasonable treatment, pregnancy can be considered as usual. 2. You must choose the right time to get pregnant (your doctor will help you judge and choose the right time). During pregnancy, nephritis is likely to worsen. The condition is also likely to worsen within six months after giving birth to a child. The fetus of lupus nephritis patients is more prone to miscarriage, premature birth, stillbirth and stunting than ordinary fetus. Therefore, it is very important to choose the right time. 3. When anti-SSA/SSB antibodies are positive, antiphospholipid antibodies are positive, proteinuria is high and blood pressure is high, the pregnancy process especially needs corresponding careful treatment. The specific program of its treatment is very different from the usual. 4. When you are pregnant, it does not mean that you can’t use any medicine. On the contrary, there is a lot of evidence to show that the rational use of medication, even some drugs with instructions that are “prohibited for pregnant women”, can be beneficial to both the mother and the fetus. In addition, it takes a long 10 months to carry a child, and the choice of drugs varies from period to period. 5, the nutrient supplementation during pregnancy, and the general population is different, should pay more attention to the use of calcium and vitamin D, more attention to the prevention of anemia. 6.After the birth of a child, it is not true that “if you take medicine, you cannot breastfeed your child”. For those who wish to promote mother-child bonding and breastfeeding, they can use the medication reasonably and breastfeed while taking the medication to maintain a long-lasting cure. 7. The process of pregnancy requires joint efforts and sharing among patients, rheumatologists and obstetricians in order to reach the ideal shore.