Ping, a 14-year-old girl from Hainan, was diagnosed with SLE two years ago, and her symptoms were slightly relieved after treatment, but she failed to follow up regularly for financial reasons and did not receive standard treatment, and also used folk remedies during the period, which eventually led to deterioration of her condition and complications such as renal insufficiency and pneumonia, and she was in a coma. At the beginning of this year, Ping was sent to the Second People’s Hospital of Guangdong Province for rescue. After treatment, Ping, who had been in a coma for 9 days, finally turned to safety and her condition improved, and will be discharged from the hospital in the near future. Doctors reminded that patients with lupus erythematosus should be prepared to fight a “protracted war”, pay attention to systematic treatment and regular follow-ups, and do not increase or decrease the amount of medication or stop it without authorization. Unauthorized discontinuation of medication led to deterioration and fainting for 9 days In February 2012, Xiao Ping, who was attending school, developed recurrent fever, joint pain and facial erythema. After being diagnosed with SLE at a local hospital, doctors treated her with hormones and immunosuppressants, and her symptoms subsided. However, because of financial reasons, Xiao Ping failed to follow the instructions for regular follow-up. In January 2013, she developed swelling in both lower limbs and then came to the outpatient clinic of the Department of Rheumatology and Immunology of Guangdong Second People’s Hospital, where she took oral medication every month for nearly a year. The doctor repeatedly advised the patient’s parents to return to the hospital twice a month for immunosuppressant injections to control the disease, but for financial reasons, Xiao Ping did not return to the hospital for regular follow-ups, resulting in a prolonged illness. In 2014 alone, Ping was hospitalized 3 times, the heaviest one being in November 2014, when she was re-admitted to the hospital with fever, general swelling and coma. During her hospitalization, she developed epilepsy and was diagnosed with systemic lupus erythematosus, lupus nephritis, neuropsychiatric lupus, renal insufficiency, thalassemia, severe anemia, hypoproteinemia, left lung pneumonia, etc. She was in a coma for 9 days. Social workers were stationed in the ward to raise money and pray for the patient. During the 9 days when Ping was in a coma, doctors treated her with hormones, immunosuppression, anti-inflammation, diuresis and swelling, and blood transfusion. However, due to her critical condition, she required high doses of hormone shock therapy and expensive drugs such as albumin, gammaglobulin and blood transfusions, which may be life-threatening if complications such as pneumonia and kidney failure occur. The use of a large number of high-priced drugs has put a heavy financial burden on Ping’s family. In order to help Ping raise money, the doctor decided to ask for help from Guangzhou Paisen Social Work Resource Center in Haizhu District. Thanks to the efforts of the social worker, the Guangzhou Weibo Children’s Welfare Foundation provided financial support to Xiao Ping. With the joint efforts of everyone, Xiao Ping, who had been in a coma for 9 days, finally came to her senses recently and her condition has improved. Reminder: SLE patients should not stop medication without authorization Many SLE patients stop taking medication because of the improvement of surface symptoms during treatment, and it is very dangerous for SLE patients like Xiaoping to stop medication without following medical advice. For patients with SLE and other rheumatic diseases, they should be prepared to fight a “protracted war”, establish confidence in overcoming the disease, always pay attention to the changes of the disease, review the disease regularly, listen to the doctor’s guidance, and do not arbitrarily reduce the amount of medicine or even stop the medicine.