There are about a dozen types of cancers that can be treated with immunotherapy, the earliest of which are melanoma, kidney cancer, sarcoma, and solid tumors such as lung cancer, stomach cancer, and colorectal cancer. Immunotherapy is now becoming more and more broad-spectrum with less toxic side effects, but during the process of immunotherapy, patients must be screened and the indications and contraindications of immunotherapy must be strictly controlled. The side effects of immunotherapy, when they occur, are likely to be fatal. For example, interstitial lung changes, interstitial pneumonia, and myocardial damage can increase the mortality rate of the patients treated. Throughout the treatment process, doctors will control its indications and toxic side effects, and they should also communicate well with patients and families in a timely manner during the treatment process. The prospect of immunotherapy is very good, and with the continuous clinical research, immunotherapy may have new breakthroughs in all kinds of solid tumors.