The generic name of Bactrim is Mupirocin Ointment, and the skin will not dry out with Mupirocin Ointment. Mupirocin ointment belongs to the group of topical antibiotics and is mainly used for skin lesions caused by gram-positive cocci infections, such as folliculitis, boils, impetigo, eczema co-infections, and ulcer co-infections. Adverse effects of the drug are mainly irritation at the site of application, such as burning sensation, tingling sensation itching, etc., so it usually does not lead to dry skin. Allergy to the drug or other excipients is prohibited. If you have a medical condition, you should consult a doctor and use the drug under his supervision. If you have dry skin, you need to have a further examination to find out the cause of the condition and actively treat it.