Osteoarthritis medication has diarrhea, consider the occurrence of adverse drug reactions, it is recommended to stop the drug and consult a doctor immediately. Adverse drug reaction refers to the harmful reaction unrelated to the purpose of medication that occurs under the normal dosage of qualified medicines. Osteoarthritis medication has diarrhea, may be taking the medication for osteoarthritis appeared adverse reaction, caused by the digestive system of diarrhea, should first stop the drug, observation for a period of time. If the diarrhea is relatively mild, after stopping the drug, the diarrhea gets better, then no special treatment. For milder adverse reactions, the body is generally able to tolerate them gradually, and a change of medication may be considered, but close attention should be paid to the adverse reactions. If the diarrhea does not improve after stopping the medication, it is recommended to contact your doctor immediately to explain the situation. Medication should be administered under medical supervision, avoid self-medication.