There is no exact value for how long can one live after surgery for middle and late stage rectal cancer, and the five-year survival rate is 5%~60%, which needs to be analyzed in the light of the condition, and there is a big difference between individuals. Rectal cancer is a common intestinal malignant tumor, which can be caused by heredity, gene mutation and other factors. After surgical resection, postoperative adjuvant radiotherapy and targeted therapy, patients with middle and late stage can achieve a five-year survival rate of 5%~60%, and the prognosis is better if the staging is earlier and the patients are more tolerant to the treatment. After the operation, pay attention to regular review as prescribed by the doctor, and consult the doctor in time for any changes in condition or discomfort. Maintain good living habits in daily life, etc., in order to reduce recurrence and prolong the survival period.