A drug like methylcobalamin is certainly fine for diabetics because methylcobalamin is essentially the active form of vitamin B12. Diabetic patients often have a state of vitamin B12 deficiency in many cases, so supplementation with methylcobalamin is necessary. For patients with combined complications, especially neuropathy, methylcobalamin can be a direct drug of choice, because methylcobalamin for neuropathy can achieve pharmacological effects from the perspective of etiology as well as symptom relief. From the perspective of etiology, methylcobalamin can replenish the raw materials in the process of nerve repair and facilitate the recovery of nerve function, while from the perspective of symptom relief, methylcobalamin can improve the symptoms of patients’ nervous system, such as pain and numbness, by supplementing vitamin B12. Therefore, methylcobalamin is important for diabetic patients, and many patients have the habit of taking methylcobalamin, which is more recommended.