Aspartate aminotransferase usually refers to aspartate aminotransferase. Low aspartate aminotransferase does not usually require specific treatment, but penicillin can be used as directed by the doctor in case of associated infections caused by sensitive bacteria. Aspartate aminotransferase is one of the indicators of liver function test, generally low aspartate aminotransferase does not have special clinical significance, no medication is needed, and it is considered to be related to the lack of physical exercise, nutritional deficiency and other factors. It is recommended to improve other related examinations, and at the same time, regular daily routine, strengthen physical exercise and nutritional supplementation. Penicillin is a β-lactam antibiotic, mainly used for intramuscular injection or intravenous drip. It is suitable for mild and moderate infections caused by penicillin highly sensitive pathogens, such as abscess, bacteremia, pneumonia, endocarditis, etc.. Some patients using penicillin may have allergic reactions, rash, asthma attacks, and even can also lead to anaphylaxis, penicillin drugs or procaine allergy patients need to prohibit the use of. For patients who meet the indications for penicillin, but have low aspartate aminotransferase can be used under the guidance of a doctor, and generally does not affect the treatment of penicillin. However, for those with concomitant penicillin allergy, use should be prohibited. Penicillin belongs to prescription drugs, before using the drug should be described to the doctor in detail their underlying diseases, physical condition, etc., in order to rule out contraindications to the use of the drug, to avoid the risk of serious use of the drug.