When adrenal cortical nodular hyperplasia occurs, the specific treatment should be decided according to the nature of the disease, and it is recommended to consult the doctor in time for further examination, and then use relevant drugs such as adrenocorticotropic steroids under the guidance of the doctor, or take surgical resection and other methods for treatment. 1. Drug treatment: if the patient is due to prolonged hyperadrenalism leading to adrenal cortex nodular hyperplasia, generally in the early stage, under the guidance of the doctor to use adrenal cortical steroid hormone drugs for treatment, and if necessary, can be used in accordance with the medical advice of the use of hydrocortisone and other medications to carry out treatment. 2. Surgery: For patients with congenital adrenocortical hyperplasia or secondary adrenocortical hyperplasia, surgical resection is required under the guidance of doctors. Once adrenal cortex nodular hyperplasia occurs, patients should go to the hospital in time to find out the cause of diagnosis and treatment, to avoid delaying the condition and leading to adverse consequences.