In general, mitral valve prolapse with moderate regurgitation is more serious and requires active treatment to avoid further impairment of cardiac function. Prolapse of the anterior mitral leaflet refers to the prolapse of the mitral valve into the left atrium during cardiac systole accompanied by prolapse of the mitral leaflet into the left atrium, accompanied by partial regurgitation of blood flow into the left atrium, which may be caused by rheumatic cardiac valvulopathy or myocardial infarction, and it belongs to the pathological changes of cardiac structure, which is a kind of organic lesion. Prolonged anterior mitral valve prolapse with moderate regurgitation may lead to heart failure, which may be accompanied by pain in the anterior chest area, palpitations, weakness, and shortness of breath. Therefore, mitral valve anterior leaflet prolapse with moderate regurgitation is more serious and requires prompt medical attention and active treatment with doctors.