There is a relationship between headaches and blood pressure. Patients with headache can cause elevated blood pressure; if the patient’s blood pressure is elevated, it can also cause the patient’s headache, nausea and vomiting. If the patient’s blood pressure is elevated due to headache, the main treatment should be given for pain relief, which can be oral ibuprofen, acetaminophen, naproxen, or oral aspirin, and the above mentioned medications are mainly suitable for patients with primary headache. If the patient is due to certain causes of headache, such as intracranial organic lesions, craniocerebral tumors, and cerebrovascular diseases, including cerebral hemorrhage, subarachnoid hemorrhage, caused by organic lesions are mainly given to the cause of the treatment, and at the same time, the patient’s blood pressure should be controlled, and generally should be applied to the levothyroxine amlodipine, amlodipine benzenesulfonate long-lasting blood pressure-lowering drugs. If the patient’s headache is caused by elevated blood pressure, the first step is to give blood pressure lowering treatment. After the blood pressure is controlled, the patient’s headache may be relieved. Commonly used blood pressure-lowering drugs include levamlodipine, amlodipine benzenesulfonate, and valsartan and irbesartan can also be applied.