Prolonged failure to form stools may be caused by gastrointestinal dysfunction, colitis, tumors, etc. It can be treated with Trimethoprim Maleate Tablets, Sulphasalazine, Glucocorticosteroids and so on. 1. Gastrointestinal dysfunction: abnormal intestinal function caused by physiological, psychological and social factors, can be treated with Trimethoprim maleate tablets, montelukast, loperamide and other drugs. 2. Colitis: Inflammatory diseases of the colon caused by a variety of reasons, such as ulcerative colitis, Crohn’s disease, etc., can be treated with drugs such as Sulfasalazine, Prednisolone and Azathioprine. 3. Tumor: Tumor inside the intestines, such as colorectal and rectal cancer, which leads to difficulty in stool formation, preferred surgical treatment, can be supplemented with targeted drugs such as bevacizumab and cetuximab to treat. When the stool is not shaped for a long time, you should have a timely examination to clarify the cause of the disease, choose the appropriate drugs and treatment, and follow the doctor’s prescription.