Gray hair on both sides of the head can be caused by physiological reasons, but also by disease factors, drug factors, malnutrition and other pathological reasons. 1. Physiological reasons: with age, the two sides of the head will grow physiological gray hair, in addition, long-term stress, mental tension and other factors can also lead to the growth of gray hair. 2. Pathological causes (1) Disease factors: If you suffer from albinism, it can be accompanied by symptoms of skin and body hair whitening. Some acquired diseases (such as vitiligo, hyperthyroidism, etc.) can also appear white hair. (2) Drug factors: If you take antimalarial drugs (such as chloroquine, artemisinin tablets) or tyrosinase inhibitors (such as imatinib, axitinib, etc.) for a long period of time, it can also lead to melanin synthesis disorders, which can lead to gray hair. (3) Malnutrition: Zinc, copper and other trace elements are necessary elements for melanin synthesis, and a lack of these substances can lead to melanin synthesis disorders, resulting in the appearance of gray hair. If there is an unexplained gray hair, exclude the physiological causes of the basis, we should go to the hospital as soon as possible, to determine the cause of the disease for timely treatment.