Urine protein 1 + normal renal function, may be caused by nephritis and other pathological factors, but also may be caused by strenuous exercise, fever and other physiological factors. 1. Pathological factors: nephritis, related to autoimmune disorders and genetic factors, no obvious symptoms in the early stage, with the development of the disease will cause proteinuria, body edema, and blood in the urine, etc., if it does not affect the renal function, most of the patients with renal function is normal. 2. Physiological factors: (1) If patients drink less water in recent times, or strenuous exercise, it will lead to a transient increase of protein in the urine, so that the patients appear to have urine protein 1+ and normal renal function. (2) fever: fever will lead to an increase in body temperature, the aggravation of the disease will cause dehydration, resulting in temporary urine protein, so there will be urine protein 1+, normal renal function phenomenon. Urine protein 1 + normal renal function may also be caused by urinary tract infections, diabetic nephropathy and other diseases, it is recommended that the patient timely hospital consultation, identify the causes, symptomatic treatment.