Acute exacerbation of chronic carrier disease, transaminases soaring dozens of times, jaundice, even acute liver failure, is a heavy blow to the liver cells, the condition is dangerous. Emergency hospitalization by liver protection and enzyme reduction after remission, the virus are significantly reduced, the E antigen may turn negative, and a few even clinical hepatitis cured. I am 25 years old. “Triple sun” chronic carrier, in June 2014 due to late night, all-night drinking and dietary discomforts, the onset of aminotransferases more than 1500U / L, the virus 4 times (unspecified units). After one month of liver protection and enzyme reduction, liver function was normalized. After that, every 3 months to check the liver function, once every six months ultrasound, now the transaminase is normal, bilirubin is a little higher, the rest are normal. (2015-11-23) A: may be the original “triple sun” chronic hepatitis B virus asymptomatic carries, the virus level has been low, suddenly acute exacerbation of the condition, aminotransferase soared to more than 30 times the normal high value. May be hospitalized by hanging bottles of liver protection to reduce enzymes (did not mention antiviral therapy), 1 month later recovery, regular review for nearly 1.5 years, self-reported “bilirubin is a little higher, the rest are normal,” the follow-up did not specifically describe the aminotransferase should be normal, the E antigen and the virus is negative, at least has been a “small triple yang “Stabilized inactive carrier. Acute exacerbation of the disease, can be due to immune stimulation, clearance force suddenly enhanced, a large number of destruction of infected hepatocytes, the virus is also the same, although the liver suffered a great deal of blow, the virus and its antigens will be almost all significantly reduced. Patients with milder disease can maintain immunity, a few may even end up carrying; most of the hepatoprotection and enzyme-lowering inflammation is relieved, hepatocytes are rapidly renewed, a large number of expanding the space for viral replication, such as timely antiviral treatment, can soon go back to the original state of carrying. My lover is 29 years old. She is 29 years old and has “small triple Yang” with normal liver function. Married for more than a year without pregnancy, in a local clinic of an old Chinese medicine practitioner took Chinese medicine to adjust 5 months when pregnant. Liver function was normal in one and a half months of pregnancy. four months pregnant in September 2014, symptoms of yellow urine and yellow eyes appeared, admitted to the local hospital for treatment, glutamic acid 620, glutamic acid 1200 U/L, total bilirubin 169 μmol/ml, HBV-DNA 7.20E+06 (unspecified unit). Diagnosed as chronic hepatitis B (severe), oral tibivudine, and enzyme-lowering and hepatoprotective treatment. The patient had a spontaneous abortion in January of treatment. (2015-11-23) A: Pregnancy does not increase the burden on the liver, and most of the hepatitis morbidities and conditions in pregnancy are the same as in normal people. Acute exacerbation is an occasional misfortune, but it can be very harmful to the fetus. Half of the genes of the fetus come from the father, which is equal to half of the fetus being a xenograft. The immune state in normal pregnant women tends to inhibit the rejection of the fetus (i.e., decreasing immune clearance); hepatitis tends to be a period of immune clearance of the hepatitis B virus, and acute exacerbation of the disease is accompanied by a sudden increase in clearance, which can trigger miscarriage. Tenofovir must be taken as soon as possible when hepatitis occurs during pregnancy. 32 years old. 2012 jaundice hepatitis, liver protection and enzyme reduction after recovery. 2014 July 28 liver disease relapse hospitalization examination “triple sun”, virus 7 times (unspecified unit), glutamic acid enzyme 2007, glutamic acid enzyme 1609 U/L, total bilirubin 102 μmol / ml, alpha-fetoprotein 362 ng / ml. Prothrombin time 20.7 seconds, platelets 80,000/μl. liver scan elasticity value 40.5 kPa. spleen thickness 5.3 cm. diagnosis of acute liver failure, transfusion of hepatoprotecting and enzyme-lowering drugs, oral entecavir. He was discharged from the hospital on September 1 with gradually normalized aminotransferases, gradually decreased total bilirubin to 23 μmol/ml, gradually normalized alpha-fetoprotein to 3.2 ng/ml, and gradually shortened the prothrombin time to 15.4 seconds, with platelets returning to 132,000/μl. Recently, the elasticity of the liver scan was found to be 10.6 kPa, and the liver is still “triple positive” but virus negative. Still “triple positive”, but virus negative. (2015-06-08) A: “chronic carry” super strong immune clearance, acute exacerbation of the disease, can be followed by the emergence of jaundice (total bilirubin > 85 μmol / ml), and continue to deteriorate can be the occurrence of acute liver failure (eg, alcoholism), most of which is caused by the potential for cirrhosis, a few less severe chronic hepatitis, and even chronic inactive Carrying patients occurs, can have some kind of trigger, or can be spontaneous. Acute liver failure from chronic liver disease, referred to as “slow-onset”, is diagnosed by a spike in aminotransferases, a daily increase in total bilirubin of >17 μmol/ml, and a prolongation of the prothrombin time of >5 seconds, which is a very dangerous condition. Emergency hospitalization, urgent liver protection and enzyme-lowering treatment is necessary! Timely and correct symptomatic treatment! Simultaneous antiviral: entecavir is safer; tenofovir is more rapid, but its nephrotoxicity must be closely monitored. If timely and accurate resuscitation, generally can return to the origin of the lesion before the occurrence of liver failure; a few may virus and its antigen turn negative. Please note: many people on the condition of the examination of the project, regular and so on very irregular, do too much medicine has not yet appeared, a waste of money, but buy unnecessary trouble; and certain necessary items are not checked, affecting the condition, the efficacy of the judgment.