HRD Positive, a result of the HRD (Homologous Recombination Repair Defective) tumor marker test, is available by blood draw. Homologous recombination repair defects, which occur when there is a double-strand break in the DNA because the cell does not have the ability to repair the broken double-strand, are often considered to be an important factor in ovarian cancer. The presence of HRD-positive patients accounts for about 53% of ovarian cancer patients in high-grade plasmacytoid ovarian cancer. HRD testing is able to detect the characteristics of gene mutations, thus assisting in clinical diagnosis, and has the clinical significance of predicting the risk of the disease, thus reducing the incidence of ovarian cancer. For HRD-positive ovarian cancer patients, the cause of its development is usually considered to be related to genetic factors, and may also be related to hormone level changes, endometriosis and other factors, and in the late stage, it often manifests symptoms such as lower abdominal discomfort, abdominal distension, loss of appetite, etc., and some patients may suffer from emaciation, anemia and irregular vaginal bleeding, which need to be further perfected with pathological and histological examination, ultrasonography, laparoscopy, etc., in order to clarify the development of the disease. further pathological histologic examination, ultrasonography, laparoscopy, etc. are needed to clarify the development of the disease. If timely drug intervention is used, the cancer cells will repair themselves through base excision repair. At this time, PARP inhibitors can be used, which can block this process and prevent the homologous recombination repair and base excision repair of the cancer cells from being realized, so as to achieve the purpose of killing the cancer cells. In addition, surgical treatment, chemotherapy, radiotherapy and targeted therapy are also available, which can be chosen under the guidance of doctors. Since there are no obvious symptoms in early stage of ovarian cancer, it is not easy to be detected, and untimely treatment will easily lead to poor prognosis, metastasis and recurrence, and HRD test can help to detect and diagnose the disease, which has certain clinical significance.