Locally advanced laryngeal cancer can be treated by surgery, radiotherapy and chemotherapy. 1. Surgery: locally advanced laryngeal cancer with proximal metastasis and lymph node metastasis can be palliatively treated by surgery, while stage 3 and 4 can still choose surgery for treatment. 2. Radiotherapy: after surgery, radiotherapy can be combined with radiotherapy, especially for patients with distant metastases. 3. Chemotherapy: chemotherapy can also be carried out after surgery according to the patient’s condition and pathological staging to further shrink the tumor so as to achieve the purpose of long-term survival, or chemotherapy can be carried out first and then surgery can be carried out after the tumor shrinks. For patients with locally advanced laryngeal cancer, it is recommended to consult ENT department of regular hospitals.