Facial rejuvenation methods currently affirm the efficacy and safety of the following methods, but also according to the different circumstances of the individual to choose: 1, young people who appear fine wrinkles, such as forehead lines, corner lines, frown lines, etc., can use Botox local injection, safe and effective. 2, skin relaxation of middle-aged and elderly people, should perform surgical methods to remove wrinkles, such as the outer corners of the eyes to enhance the corners of the eyes at the same time coarse wrinkles can also be improved. 3, large wrinkles such as the decree lines and large interbrow lines, can be localized injection filler, including the use of hyaluronic acid, autologous fat, etc.. Sometimes it is necessary to focus on several methods at the same time may have better results. Each of the above methods should pay attention to his risks: 1, injections of botulinum toxin should pay attention to allergic reactions, which will recover soon after timely discovery of treatment, and also cannot be injected in large quantities. 2, wrinkle surgery are risky, pre-operative strict indications and necessary checks, careful operation during surgery, careful care after surgery, generally can be avoided. 3, injectable filler (microplasty) pay attention to absolutely do not enter the blood vessels, the consequences of facial vascular embolism is very serious, there have been reports of cosmetic injections leading to blindness and intracranial vascular embolism.