After taking the cold particles cold symptoms did not improve should be based on the individual’s condition as well as the actual medication to deal with, such as medication course of insufficient people can adhere to continue to take medication, in the case of the individual’s physical quality is relatively poor or the condition is more serious can be considered a combination of medication. 1. Adhere to continue to take medication: the treatment of colds is not an overnight thing, it is not that the individual after taking a cold spirit particles, the symptoms will certainly be relieved, the course of treatment is insufficient is likely to have a cold symptom does not improve the situation, so the individual needs to do the full amount of full course of treatment, in order to get good results. 2. Combination of drugs: In the case of poor physical quality and more serious conditions, the effect of simply taking cold and flu particles may not be very effective, so individuals can consider a combination of drugs, such as cough syrup, dextromethorphan, aminobromine dispersible tablets and so on. 3. Causative medicine: If influenza is caused by influenza virus, anti-viral treatment with oseltamivir and other medicines is needed; if combined with or secondary to bacterial infections, antibiotics such as cephalosporin, amoxicillin, macrolides and other antibiotics are needed; other illnesses, such as tuberculosis and acute infectious diseases, can also cause cold-like symptoms, and isoniazid and other therapies need to be used causally. The use of Cold & Flu Granules may cause some adverse reactions, such as drowsiness, thirst, feeling of weakness, etc. Long-term use of large quantities of medication can also cause liver and kidney dysfunction. Severe liver and kidney insufficiency should be forbidden to use Coldling Granules. It is recommended to consult a doctor in time to improve the relevant laboratory tests, to exclude the possibility of combining with other diseases, the use of medication should be in accordance with the doctor’s instructions, do not take medication without authorization, so as to avoid aggravation of the condition.