Two patients were recently treated surgically after radiotherapy for lung cancer. 1 case Wang** Male 57 years old Squamous carcinoma of the upper lobe of the right lung The patient’s lung cancer was discovered in 2009 Pathology was diagnosed by endoscopic ultrasound guided transesophageal lung fine needle aspiration biopsy. The patient was treated with 6 cycles of chemotherapy with GP regimen and paclitaxel and other regimens. At the same time, the patient was treated with appropriate radiotherapy to the chest. This year, the size of the lesion was reduced but the density was still high. The patient was discharged successfully. The patient was discharged successfully. 2 cases Male Song** 52 years old Diagnosis: left lung squamous carcinoma The patient was treated with NC regimen chemotherapy for 6 cycles and chest radiotherapy The main body of the lesion did not disappear. Left total pneumonectomy was given. Surgery went well. In summary, the indications for lung cancer surgery can be relaxed according to the patient’s treatment condition. Pre-operative assessment of the tumor volume and the surrounding vascular relationship lung function, etc. It should be noted that when separating blood vessels, it must be sharply separated, because the normal vascular epithelium is thickened without normal anatomical structure after radiotherapy. Do not use excessive force to prevent cutting when ligating.