High-risk HPV type 16 positivity is also clinically possible to have intercourse. For high-risk HPV infection it is still clinically important to pay attention to it. It is recommended that colposcopy should preferably be done 3-7 days after menstrual cleansing. The main purpose is to understand whether the cervical epithelium is diseased under high-risk HPV infection, so colposcopy is needed. In case of positive colposcopy result, pathological examination is needed to take down the local tissue material of the cervix and send it for pathological examination and clinical and pathological diagnosis prevails. Because persistent infection with high-risk HPV 16 may lead to precancerous lesions of the cervical epithelium and even to cervical cancer, and most cervical cancers in Asian women are caused by high-risk HPV 16 infection and high-risk HPV 18 infection, so clinical attention should be paid to this viral infection.