The symptoms of advanced liver cancer are more obvious, such as wasting, swelling of hands and feet, slurred speech, rapid heartbeat, fever, abdominal distension, diarrhea, and vomiting blood in severe cases, and the symptoms of advanced liver cancer before death are usually not very different.
The treatment methods of advanced liver cancer include
1.Surgical treatment
Surgical treatment is the traditional method for treating liver cancer at present. In recent years, due to the updated progress of early diagnosis, localization diagnosis, tumor biology and several concepts of liver cancer surgery, especially with the means of integrated treatment with traditional Chinese medicine, the effect of liver cancer surgical treatment has been significantly improved. The main ones include the following.
(1) Surgical resection treatment
(2) Various intraoperative local treatments that cannot be resected: (1) intraoperative hepatic artery portal vein chemotherapy and ligation; (2) infusion chemotherapy with drug injection pump; (3) intraoperative microwave radiation therapy; (4) intraoperative cryotherapy; (5) intraoperative electrochemical therapy; (6) triamcinolone acetonide liver infusion chemotherapy; (7) sequential treatment of liver cancer.
2.Radiotherapy
With the progress of research in radiation physics and radiation physiology in recent years, radiotherapy equipment has been further improved, such as cobalt 60 gamma rays or X-ray of electron linear gas pedal and high-energy rays. The effect of radiotherapy for liver cancer has been significantly improved, and the side effects have been reduced to the lowest level.
3.Chemical drug treatment
As 95% of liver cancer patients have lost the opportunity of surgery at the time of diagnosis, most of them still depend on chemotherapy. In the past, chemotherapy for hepatocellular carcinoma was not highly evaluated, especially the efficacy of systemic administration was very low. At present, it is considered that intubation chemotherapy is better than systemic combination chemotherapy and combination chemotherapy is better than single drug chemotherapy. Hepatic artery cannulation chemotherapy is considered to be the best treatment for patients with hepatocellular carcinoma who are not suitable for surgical treatment.
4.Interventional radiology treatment
Interventional radiology techniques of percutaneous super-selective hepatic artery infusion chemotherapy and embolization, which emerged in the 80s and developed rapidly, play a crucial role. Whether it is early stage limited hepatocellular carcinoma or middle or late stage hepatocellular carcinoma treatment, this interventional radiology technique is a decisive treatment method and essential.
First of all, when liver cancer is advanced, the tumor is still formed and most patients are no longer suitable for surgical resection at this time, so interventional treatment is recommended. For advanced liver cancer that is no longer resectable by surgery, the survival rates of interventional treatment at 1, 3, 5 and 7 years are 82%, 57%, 39% and 21% respectively, and the median survival time is 43 months.
If you want to choose surgical resection, but the tumor is at the upper limit of surgical resection, the risk factor is very high, you can use interventional therapy to treat the tumor, because after interventional therapy, 99% of patients will have the tumor shrunk by 2~5 cm.
5.Immunotherapy
In China, BCG, small rod-shaped bacillus, levamisole, tumor vaccine, embryonic cells, thymidine, transfer factor, immune ribonucleic acid, etc. have been tried, but they have not been effective. Interferon, interleukin-II and lymphokine-activated killer cells have been used more frequently in recent years, which can improve the therapeutic effect of hepatocellular carcinoma to different degrees alone or in combination with other therapies.
6.Molecular targeting therapy
Sorafenib (Doxorubicin), Sotan, Avastin, Endo and so on. It can slow down the tumor progression and prolong the survival period. Sorafenib can prolong the survival time of patients up to several months or even longer.
7.Chinese herbal medicine treatment
Systematic herbal treatment can increase the immunity of patients, reduce the discomfort of cancer patients, shrink the tumor and improve the overall quality of life of patients to prolong their lives.