The difference between the urethra and the vagina lies in the different systems to which they belong, their different locations and their different functions. 1. Different systems: the urethra belongs to the organs of the urinary system, and the vagina belongs to the organs of the reproductive system. 2. Different positions: the urethra is connected to the bladder and kidneys, and the external opening is below the clitoris and above the vagina; the vagina is connected to the uterus and fallopian tubes, and the external opening is below the urethral orifice and above the anus. 3. Functions are different: the urethra is a tube for discharging urine; the vagina is a channel for sexual intercourse, discharging menstrual blood, and delivering a fetus. Women should pay attention to maintain pubic hygiene, often wash the vulva; change underwear, wear loose breathable underwear; good menstrual care, prohibit menstrual sex and masturbation, to avoid pathogen infection. If women have symptoms of vaginal discomfort, they should go to a regular hospital in time and be treated under the guidance of a doctor so as not to delay their condition.