Rectal administration is relatively safe and may cause some degree of damage to the rectal mucosa if not done properly.
Because of the poor cooperation of children, in the clinical part of the drug can choose rectal administration, such as in the clinical choice of antipyretic drugs such as diclofenac sodium suppository. Compared with other routes of administration, there are fewer adverse effects, and the pain of injection can be reduced, especially in children who do not cooperate with oral medication, and there is a rectal route of administration that can be chosen.
Rectal administration of drugs in the clinical almost no side effects, because rectal comparison is relatively safer than oral, rectal administration of drugs into the rectum, after the rectal mucosa, through the rectal mucosa directly absorbed, to avoid the first-pass effect of the drug, do not need to enter the hepatic and intestinal circulation to play a role in the liver, the liver is generally not a burden.
Rectal administration of drugs, parents improper operation or excessive force, may cause rectal mucosa bleeding caused by erosion and other problems, so it is recommended to move gently, if necessary, you can consult the regular hospital anorectal doctor.