“The junction of the two yangs is called elimination” is from the article “Suwen – Yin and Yang Bie Lun”. This original text is often quoted and guides the treatment of thirst-quenching disease in traditional Chinese medicine (TCM). Whether from the literature of the past generations or from personal experience, this scripture does have its profound guiding significance. Then, how to solve the “two yangs” and what does “knot” mean? “Two Yang knot, said the stomach and large intestine are hot knot. Stomach and intestines hide heat, then like to eliminate water and grain.” Here is very clear, two Yang refers to Yangming, can be foot Yangming stomach, can also be hand Yangming large intestine, or both together. The word “knot” is interpreted as “heat knot” by Wang Bing. So how do we understand “heat knot”? The more common understanding is “heat and persistent dirt fighting into a firm knot”, that is, the bowels do not pass. Clinically, many diabetic patients, especially those in the early stages of diabetes, have constipation, and there is a correlation between the control of blood glucose and the smoothness of their bowel movements. In the “Golden Chamber” book “thirst solution” chapter, pointed out that “the Golden Chamber” thirst a, the preparation of a prescription theory, are the “Neijing”, the most pure method. And that “Jin Gui” thirst chapter, “tarsus yang pulse number, there is heat in the stomach, that is, thirst and lead to drink, stool must be firm, urination is a number of” and “tarsus yang pulse floating and counting, floating is the gas, the number of elimination of grains and large firm” of the discussion, is precisely “two Yang knot”, “is called the elimination of”, and that “tarsus yang pulse floating and counting, floating is gas, number of elimination of grains and large firm. This is the most appropriate explanation of “the knot of two yangs is called elimination”. Therefore, in the treatment, it is suggested that “the treatment should be to remove its firm knot and clear its accumulated heat, therefore, the middle elimination can be down”. The opinion of the And respected the method of regulating the stomach and Cheng Qi slow down. For “long time fluid has been injured, the knot heat does not go, intestinal fluid, firm knot can not go down”, it can be given to Ma Ren, moist and dry TongYu, HuangLong, YuMei, increase liquid and so on, in order to achieve the “positive is not hurt and knot to go,” the therapeutic purpose. At the same time, it is pointed out that “if you use purging heat, the knot does not go, then the heat breaks clear; use generating fluids, the heat is not clear, then the fluids will not be recovered” is the clinical need to avoid the therapeutic misunderstandings.