Redness, swelling and burning of the upper lip may be caused by neurovascular edema, herpes labialis or labiitis, related to exposure to allergic substances or bacterial viral infections. 1. Neurovascular edema. When the lips come into contact with allergens, or take allergic substances can lead to neurovascular edema of the lips, the localization will be immediately swollen, red and itchy, you need to immediately stop contact with allergens, take anti-allergy drugs (loratadine). 2. Herpes labialis. When infected with herpes virus can cause herpes labialis, localized redness, swelling and blisters on the lips, and then break out and become infected. Need to take antiviral drugs, such as acyclovir, ribavirin. 3. Lip inflammation. Upper lip redness and burning may also be caused by lipitis, the performance of a variety of flaking, cracking, redness and burning, often associated with local irritation, may also be related to the body’s immune system, can be applied locally antibiotic ointment to prevent secondary infections. The redness and burning of the upper lip can be triggered by a variety of factors, specific need to go to the hospital for examination in order to clarify the cause of the disease. Drugs should be used under the guidance of a doctor.