Itchy peeling toes, may be due to tinea pedis, contact dermatitis caused, it is recommended that the patient under the guidance of a doctor to clarify the specific cause of the disease through the topical and oral medication to carry out the treatment. 1. Tinea pedis: the toe seam peeling itchy first need to consider tinea pedis, this disease is caused by fungal infection, treatment can be used topical antifungal drugs, such as naftifine ketoconazole cream, terbinafine cream. If necessary, oral terbinafine and other antifungal drugs. 2. Contact dermatitis: Contact dermatitis of the feet may be caused by allergy to the material of shoes and socks. In the treatment of glucocorticoids such as mometasone furoate gel can be used externally, and when itching is obvious, antihistamine drugs can be taken orally, such as levocetirizine hydrochloride, olopatadine hydrochloride and so on. For the existence of toe seam peeling itchy patients, it is recommended to timely to the regular hospital examination, under the guidance of a professional doctor to standardize the treatment, the use of drugs need to comply with medical advice.