Atherosclerosis occlusive disease is a systemic disease that involves large, medium and small arteries throughout the body from day 1 of its onset, especially the large and medium arteries. Atherosclerosis can occur in various places, as follows: 1, if it occurs in the coronary arteries, angina pectoris will appear, and serious myocardial infarction will occur; 2, if it occurs in the carotid arteries, symptoms of cranial ischemia will appear, which may lead to vision and hearing loss, memory loss, and even brain infarction, and studies have shown that Alzheimer’s disease and carotid atherosclerosis are directly related; 3, if it occurs in the extremities, typical manifestations can appear, namely Intermittent claudication, the patient will walk a distance after the lower limbs will appear sore, suffocating, had to stop, stop rest will be relieved within a few minutes, this is typical of arterial claudication caused by ischemia; 4, atherosclerosis can occur in the internal organs, including the renal arteries appear renal function decline, blood pressure rise, intestinal digestive function is weakened, abdominal pain after eating, the patient wasting, etc.. Therefore, atherosclerosis is a systemic disease and will show different symptoms.