Herpes hand, foot and mouth, also known as hand, foot and mouth disease, does not usually require the administration of topical creams. If itching is present, topical glycerin lotion may be given. If there is a herpes rupture, antibiotic ointment can be used as prescribed to prevent infection. Commonly used antibiotic ointments include erythromycin ointment and mupirocin ointment, which are topical antibiotics that can be used for common bacterial infections of the skin. However, it should be noted that those who are allergic to the above drugs are contraindicated, and special groups such as pregnant women, lactating women, etc. should be used with caution. In addition, attention should be paid to the occurrence of local skin burning sensation, itching and other adverse reactions. Therefore, it is recommended that when the above diseases or symptoms occur, it is recommended to go to the hospital in time to avoid blind use of medication to avoid delays in the condition.