Sperm deformity rate of 99% is deformed spermatozoa, which may be related to certain diseases, environmental factors, and the use of drugs. Deformed spermatozoa may be related to certain diseases, such as orchitis, epididymitis, prostatitis, seminal vesiculitis, varicocele, etc. It may also be related to the testicles being in a high temperature for a long time, smoking and other bad life habits. If the patient lives for a long time in an environment with excessive heavy metals such as boron, cadmium, chromium, lead, manganese, mercury, etc., or an environment containing chemical substances such as phenoxycarboxylic acid pesticides, organophosphorus pesticides, styrene, and butylene, etc., it will also lead to dysmorphic spermatosis. In addition, long-term or high-dose use of corticosteroids, androgens, estrogens and other hormonal drugs that can lead to endocrine disruption, the use of drugs such as cyclophosphamide and vincristine, and exposure to ionizing radiation can lead to teratozoospermia. If the test reveals 99% sperm deformity, please follow the doctor’s advice to improve the follow-up examination and treatment.