High pepsinogen ratio is usually caused by H. pylori infection, peptic ulcer, gastritis and other gastric diseases. Patients may experience acid reflux, bloating and other uncomfortable symptoms, and need to go to the hospital for symptomatic treatment in a timely manner. Common causes of pepsinogen ratio are usually the ratio of pepsinogen type I and pepsinogen type II. A high ratio is mainly caused by excessive secretion of gastric acid from the main cells of the fundic glands, resulting in nausea, vomiting, acid reflux, abdominal pain and other uncomfortable symptoms, which often indicate the presence of gastric ulcer, gastritis, gastric perforation and other lesions in the stomach. Treatment measures When the pepsinogen ratio is high, the diagnosis can be clarified after upper gastrointestinal tract imaging, gastroscopy, carbon 13 or carbon 14 breath test, etc., and then the primary disease can be treated to promote the ratio to return to normal. Generally, medications such as anti-H. pylori infection, inhibition of gastric acid secretion, and promotion of gastrointestinal motility can be administered under the guidance of a professional physician. If the disease is serious, such as ulcers combined with perforation, bleeding is difficult to control, or the pylorus is completely obstructed, you can also choose the appropriate surgery for treatment according to the condition under the advice of the doctor. In terms of diet, patients need to pay attention to regular diet, and try to eat less and more, chew slowly, avoid indigestible food, spicy, greasy food, such as fried chicken, French fries, chili, etc.. Also need to do regular work and rest, pay attention to the combination of work and rest, and avoid staying up late to promote recovery.