Pepsinogen, or PG, is divided into pepsinogen I and pepsinogen II, which mainly reflect the morphology and function of the gastric mucosa at different sites. Low pepsinogen I indicates reduced gastric acid secretion, while most of pepsinogen II is elevated, and low PGⅠ/Ⅱ ratio is related to the progress of gastric mucosal atrophy, but both need to be combined with clinical symptoms and other examinations for diagnosis. 1. Low pepsinogen I: It often indicates damage to the mucosa of gastric fundus and gastric body, reduced gastric acid secretion, mostly related to improper diet and rest, alcohol consumption, drug factors, and even There is even the problem of H. pylori infection. If the patient has the above bad habits recently, it is recommended to review in two weeks, if accompanied by stomach pain, gastric distension, gastric acid reflux and other uncomfortable symptoms, it is recommended to perform gastroscopy to clarify the gastric mucosa, gastric fundus, under the guidance of the doctor to apply gastric mucosal protective agent treatment, usually also need to regulate the diet, more vitamin supplements and eat easily digestible food; 2, PG Ⅰ/Ⅱ ratio is low: pepsinogen Ⅰ, Ⅱ ratio can play The low ratio can indicate the progress of gastric mucosal atrophy. The doctor will determine the degree of gastric mucosal atrophy based on the test results, and then administer medication to promote glandular repair. Low pepsinogen is mostly related to poor living habits. It is recommended to develop good living habits in daily life, eat regularly, eat more fresh vegetables and fruits, eat less spicy and stimulating food, drink and smoke less, and pay attention to dietary hygiene. Rest more, avoid staying up late, and exercise properly to enhance body resistance.