Elderly people cry in the middle of the night with the physical factors such as being frightened, nervousness, but also consider with Alzheimer’s disease, epilepsy, depression and so on. 1. Physiological factors: If the elderly are frightened in the middle of the night or have been overstressed recently, the phenomenon of crying in the middle of the night is likely to occur. 2. Alzheimer’s disease: the cause of the disease is not yet clear, but it is considered to be related to aging, family history of disease and other factors. Typical symptoms of Alzheimer’s disease include memory loss, inattention, emotional abnormalities, behavioral abnormalities, etc., which can also be manifested as crying in the middle of the night. 3. Epilepsy: The cause of epilepsy is more complex. During seizures, patients may experience generalized convulsions, increased salivary secretion, and sudden cessation of activities. When the elderly have epileptic seizures at night, they may cry in the middle of the night due to fear. 4. Depression: the etiology is not clear, but it is considered to be related to genetic and neurobiochemical factors. Depression often causes patients to appear moody, slow thinking, reduced will activity, etc., can also be manifested in the elderly in the middle of the night crying. When the elderly long-term phenomenon of crying in the middle of the night, should be timely medical examination, in order to clarify the disease and follow the doctor’s instructions for treatment, to promote the body to restore health.