Tuberculous encephalitis, that is, tuberculous meningitis, the patient is in a coma for two months still can not wake up can not be generalized, if the patient actively for treatment, it is possible to wake up. Tuberculous meningitis is a central nervous system tuberculosis caused by the invasion of mycobacterium tuberculosis into the patient’s arachnoid membrane, which will cause continuous damage to the patient’s brain parenchyma and may be complicated by severe hypokalemia, leading to the patient’s coma. Some patients may still wake up with aggressive treatment. Firstly, during the coma period, family members should actively take the patient to the doctor for treatment, and give the patient isoniazid, rifampicin and other anti-tuberculosis drugs for chemotherapy according to the doctor’s prescription. Secondly, the condition of comatose patients with TB meningitis is usually more serious. If the doctor evaluates that the patient’s condition can tolerate surgery, the family should take the patient to undergo surgery such as lateral ventricular puncture and drainage as soon as possible. At the same time, for patients with hypokalemia, family members should also give patients potassium chloride, potassium citrate and other medications. To summarize, it is impossible to tell whether patients with tuberculous meningitis can still wake up after two months of coma, but it is recommended that patients should actively seek medical treatment to increase the chances of reawakening.