The difference between nephrotic syndrome and nephritis is as follows: first, the causes of nephrotic syndrome and nephritis are different, nephritis mostly refers to primary glomerular disease, that is, the kidneys themselves have problems. While nephrotic syndrome has both primary and secondary factors. The causes of primary nephrotic syndrome are the same as the pathological types of nephritis, which include mesangial proliferative glomerulonephritis, membranous nephropathy, microscopic lesion type and membranoproliferative glomerulonephritis. However, secondary nephrotic syndrome is often caused by problems in other systems of the body, including diabetes, hypertension, tumors, hepatitis B, hepatitis C and other common factors. Secondly, nephrotic syndrome and nephritis are different, nephrotic syndrome is often manifested as a large amount of proteinuria, edema and hyperlipidemia. Instead, the common clinical manifestations of nephritis are hematuria, proteinuria, hypertension, edema and different degrees of renal function impairment. Third, the treatment of nephrotic syndrome and nephritis is different, patients with nephrotic syndrome often need hormone combined with immunosuppressant treatment, and may also need anticoagulation and other treatments for comorbidities. The treatment of nephritis is mainly to avoid further aggravation of kidney damage, including regulating blood pressure and blood sugar, avoiding the use of nephrotoxic drugs and avoiding infection and exertion, etc. Hormone is not the preferred and recommended treatment for nephritis.