The cause of irritable bowel syndrome is still unclear, and the application of probiotic drugs can play a role in regulating the intestinal flora, improve diarrhea and other symptoms, which is helpful in improving the condition. Irritable bowel syndrome can lead to abdominal pain, abdominal distension, diarrhea, constipation and diarrhea and constipation alternating symptoms. For this disease, the main symptomatic treatment, such as for diarrhea, can follow the doctor’s instructions for the application of montelukast and other drugs for treatment; for abdominal pain, can follow the doctor’s instructions for the application of scopolamine and other drugs for treatment. In addition, patients can also follow the doctor’s instructions to apply probiotic drugs for treatment, such as bifidobacteria, lactobacillus, etc., can improve the symptoms of abdominal distension, diarrhea, correct the imbalance of intestinal flora, for the treatment of irritable bowel syndrome has a certain degree of help. It is recommended that patients with irritable bowel syndrome consult a doctor for timely examination, and take medication under the guidance of a doctor, and avoid applying medication arbitrarily.