With the progress of social productivity, human height is also increasing, which invariably causes great psychological pressure on those people who are short in stature. According to the statistics of a domestic media survey, about nearly half of the patients asked for height increase because of the difficulty in finding jobs. Because of the short stature in adulthood will bring many adverse effects on their work, study, marriage, life and psychological aspects, so some patients blindly buy commercially available so-called “height enhancement products”, in fact, most of these products are ineffective and also harmful. Therefore, people who are short in stature should not seek medical help in a hurry, but should find out what the reason for not growing taller is. Then decide whether you should use recombinant human growth hormone treatment? How much should be used? How long is the treatment course? Clarify the factors that affect the efficacy of treatment. Before deciding on a treatment plan, it is important to go to a qualified hospital for medical examination and diagnosis, so that the treatment plan can be formulated on this basis with reliable efficacy. Short stature: finding the cause is most important Finding the cause is the first and most important task. Nowadays, short stature is the most common endocrine disorder in children’s growth and development, and it is also an issue of great concern to children themselves, parents, teachers and society. However, despite this, the consultation, diagnosis and treatment of short stature in children is always too late, and often patients with dwarfism come to the doctor more than 17 or 8 years old, and although their height can increase after treatment, it is unlikely that they will reach the final average height of adults. Therefore, early detection, early diagnosis and early treatment of dwarfism are very important. It is not difficult to detect short stature, as it can be understood by measuring the growth rate of children’s height every year. If a child’s height growth rate is less than 4-5 cm per year (5 cm/year before the age of 4, 4 cm/year after the age of 7), it should be considered that there is a disorder of height development, coupled with slow epiphyseal development and bone age that is more than 2 years behind the age, it is necessary to seek medical attention early to further diagnose the cause. The most common cause of dwarfism is short stature due to growth hormone deficiency, commonly known as “dwarfism”. It is easy to diagnose through laboratory tests. A CT scan shows that there is something called pituitary gland in the pterygoid saddle of the normal skull base, which secretes growth hormone to promote epiphyseal growth, and the bone grows to both ends, and the stature will keep increasing; if the secretion of growth hormone is too little before puberty, the stature will be short. There are many other causes of short stature, including familial short stature, delayed puberty, nutritional deficiency, hypothyroidism, precocious puberty, congenital ovarian hypoplasia, chondrodysplasia and other diseases that can cause growth disorders. Short stature: the earlier the treatment, the better the effect The younger the age of starting the correct treatment, the better the effect. Studies at home and abroad have shown that children with short stature caused by growth hormone deficiency can be treated with growth hormone before the age of 3 to achieve a nearly normal and fast-growing height, and their final height is almost indistinguishable from that of normal people. However, very few patients can start treatment at the age of 3 to 4 years old, and most patients come to the clinic only after puberty because they encounter setbacks in school, job assignment, military, marriage, etc. At this time, the treatment is effective, but far less effective than the treatment when they are young. Therefore, the best time to treat short stature is from the age of 5 to before puberty. Parents should not delay the golden opportunity to treat their children with the concept of “wait and see, late growth theory”. The treatment of short stature is mainly chosen according to different causes. The goal of treatment is to maintain normal growth rate, to win rapid growth during puberty, and to reach the final height of adults. Growth hormone injections are the only effective treatment for short stature. The growth hormone currently used in clinical practice is genetically recombinant synthetic growth hormone, which is identical in structure and function to the growth hormone secreted by the human pituitary gland. At present, the US FDA has approved the indications for recombinant human growth hormone: growth hormone deficiency, idiopathic short stature, Turner syndrome, and small for gestational age children. Growing taller: what conditions must be present Whether a child’s physical growth is consistent and eventually reaches the desired height at the correct age depends on a variety of factors. Some factors are unchangeable (e.g., genetics) and some are modifiable (e.g., nutrition). Paying early attention to height problems will make half the effort. Genetic factors: height is multi-gene inheritance. If Yao Ming is tall, his parents are above 1.90 meters tall. If the parents are not tall, pay attention to the acquired environment to make up for the congenital deficiency. For those who inherit parental factors, do not have unrealistic fantasies about the final height. Ensure sleep: The secretion of growth hormone has a circadian rhythm. In normal people, 45 to 90 minutes after going to sleep, there is a very obvious rise in plasma growth hormone, which can reach more than 10 times of the daytime level. Therefore, adolescent children to ensure adequate sleep is an important factor in the growth of height, sleep every night before 10 o’clock, to ensure that the time to sleep 7 hours a day, such as children with bedwetting should be treated early, to prevent the impact on height. Exercise influence: normal people spend the night on an empty stomach and wake up in the morning with low growth hormone levels; after exercise, especially after climbing stairs, growth hormone secretion increases significantly. Sports, such as basketball, swimming, rope skipping, standing and touching, stair climbing, etc., can not only promote growth hormone secretion, but also stimulate the growth of epiphysis, so insisting on these sports from childhood can help you grow taller. Nutritional conditioning: milk is rich in arginine can stimulate the secretion of growth hormone, so once three meals with dairy products or drinking fresh milk, on the growth of taller, especially before going to bed drinking milk is more important, milk is rich in active easily absorbed calcium, also plays an important role in ossification. Fresh shrimp and sea shrimp rice is also rich in arginine. Eliminate anxiety: Anxiety and a poor family environment can affect a child’s height. Creating a relaxed, free and positive environment for your child also plays an important positive role in height improvement. Avoid obesity: Increased fatty acid concentration in the blood can inhibit the secretion of growth hormone. It has been determined that both spontaneous and stimulus-induced growth hormone secretion in obese children is inhibited, and the height of obese children is significantly lower than that of normal weight children. If children are found to be obese, they should actively reduce their weight through exercise in order to reduce the level of fatty acids in the blood and make the release of growth hormone more fluent. In summary, taller parents, better nutrition and more physically active people have taller stature, but all of these influences need to be based on physiological amounts of growth hormone. When the annual growth rate of children over 4 years old is found to be less than 4.5 cm, a growth hormone and epiphysis examination should be done, and if a deficiency is found, the earlier the supplemental treatment should be done, the better, and the supplemental growth hormone treatment after 18 years old is three times less effective. May all parents in the world create good growth conditions for their children.