Thalassemia is a hereditary disease, which is caused by an abnormality in the gene that results in impaired production of the bead protein, which leads to anemia. Patients with thalassemia are not iron deficient, iron supplementation therapy is ineffective, and if sustained iron supplementation causes iron overload in the body. In patients with iron overload there is a risk that iron deposition will lead to dysfunction in several systems, such as abnormal liver function, abnormal renal function, and neurological abnormalities. Iron deficiency patients only need to carry out iron supplementation therapy, the clinical mainly for iron deficiency anemia patients for iron supplementation therapy, and iron therapy is not lifelong, but after the removal of the cause of the disease will be stored iron to normal.