Children with fever plug fever suppository, can not eat at the same time antipyretic drugs, but for the interval of 4 ~ 6 hours of temperature recurrence of children, can be oral antipyretic drugs, such as ibuprofen suspension. General antipyretic drugs are commonly used orally or anally two ways, for children who have used antipyretic suppositories, not at the same time oral antipyretic drugs, to avoid aggravating the side effects of the drug. However, for children who have fever and stuffed with antipyretic suppositories, and then have fever again in the interval of 4 to 6 hours, oral antipyretic medicines (such as ibuprofen suspension) can be administered under the guidance of a physician for symptomatic antipyretic, which belongs to the rational use of medicines. Fever is a common symptom in pediatrics, reasonable use of antipyretics can reduce the discomfort of children due to fever, commonly used antipyretics are acetaminophen and ibuprofen, incorrect use of the drug may appear rash, liver and kidney function damage. It is recommended to consult a specialist for guidance on the use of medication.