When total cholesterol of 6.47 and LDL of 4.45 are found to be above the upper limit of the normal range, people without chronic diseases can stay off the medication for the time being, while people with pre-existing chronic diseases such as hypertension, diabetes, and coronary heart disease will need to take medication. Since the blood lipid level is affected by diet, exercise and other living habits, its level is constantly changing. For people who do not have chronic diseases, there is hope that the blood lipid level can be controlled in the normal range through strict dietary management, weight control, and exercise, and medication can be administered if the level is still uncontrollable. For people with hypertension, diabetes mellitus, coronary heart disease, cerebral infarction, carotid plaque and other diseases, their lipid targets are often more stringent, and lipid levels exceeding the upper limit of normal are likely to increase cardiovascular and cerebrovascular complications or even aggravate the original disease, and need to be treated with oral medication as early as possible. Therefore, when the total cholesterol is found to be 6.47 and LDL is found to be 4.45, it is necessary to consult a doctor in time, and after completing the relevant examinations and tests, a specialist doctor will judge whether it is necessary to take medication.