(Disclaimer: This article is only for popular science purposes, in order to protect the privacy of patients, the following content of the relevant information has been processed) Abstract: 50-year-old female patient appeared to urinary frequency, urinary urgency, anxiety to the clinic, outpatient routine urinalysis, no leukocytes and erythrocytes are not seen to be elevated. Ultrasound examination of the urinary tract did not show any significant abnormality, and increased bladder sensitivity was diagnosed after urodynamic examination. By giving medication and instructing the patient to do bladder training (urine-holding training) and pelvic floor muscle training (anal retraction training), the patient’s symptoms were relieved and her anxiety improved. Basic information] Female, 50 years old [Disease type] Enhanced bladder sensitivity [Hospital] Zhengzhou First People’s Hospital [Date of consultation] December 2021 [Treatment plan] Urodynamic examination + medication (Mirabelone extended-release tablets + antidepressant pills + levofloxacin tablets) + rehabilitation training (urine-suppressing training + retracting training) + psychological counseling [Treatment cycle] 14 days of treatment with medication and outpatient follow-up in 7 days. Review, telephone follow-up at 14 days 【Treatment effect】Symptoms relieved, anxiety improved I. Initial consultation The patient came to me one month ago for acute cystitis, at that time, the patient had frequent urination, severe urinary pain, leukocytes in the urine (++++), red blood cells (++). Oral levofloxacin tablets for 1 week after the cure, urinary frequency symptom damage reduction, but always there, during the day 1 hour to go to urinate 1 time, and once there is a desire to urinate, you have to go to the toilet immediately, can not hold it at all, the amount of urine is not much. I can’t sleep well at night, I am afraid of being woken up by urine, and I always want to go to the toilet. At home, she took levofloxacin tablets for 1 week without effect. Physical examination: no pressure and percussion pain in both kidneys, no pressure and pain in the suprapubic bladder area, normal development of the genitalia, and no abnormality of the urethral opening. After treatment, routine urinalysis was performed in the outpatient clinic, and no elevated leukocytes or erythrocytes were seen. Urological ultrasound examination did not show any obvious abnormality, and it was initially considered to be a urethral syndrome caused by post acute cystitis, because urodynamic examination is invasive and it can aggravate the patient’s symptoms. Two options were proposed to the patient, one: oral medication first, then observe the effect, if the symptoms are relieved, then there is no need to do urodynamic examination. Two: do the urodynamic examination first, and then consider the next step of the treatment plan after the results of the examination. The patient asked for a urodynamic examination and the result was: increased bladder sensitivity. Oral treatment with Mirabelone extended-release tablets and decongestant pills was recommended. The patient was also instructed to do bladder training (urine-holding training) and pelvic floor muscle training (anal retraction training), and psychological guidance was given to the patient to avoid anxiety. The patient came to outpatient clinic 7 days after treatment to review the residual urine ultrasound: no residual urine was seen. Frequent urination, urinary urgency than before to ease, basically 2 hours to urinate once, the amount of urine is also more than before, sleep at night to get up 1-2 times, continue to psychological counseling to the patient, increase the patient’s confidence. Patients continue to take medication for 1 week, telephone follow-up patient symptoms have basically disappeared. Ask the patient to stop the drug, continue to do bladder training (urine holding training) and pelvic floor muscle training (anal retraction training) can be. Precautions We are glad that the patient’s symptoms have improved after treatment, but we remind the patient that he still needs to pay attention to some matters in his daily life: 1, control the amount of drinking water, not more than 2000ml/day, reasonable arrangement of drinking water time, and less drinking water in the night; 2, you can eat more nutritious, light, easy-to-digest food with high vitamin content such as eggs, fruits, and vegetables, while high fiber content such as Cereals, mushrooms, high calorie nuts, milk, etc.; 3, try to avoid strong tea, coffee and other drinks that stimulate nerve excitation and increase the urgency of urination. In addition, alcohol and spicy stimulating food is not only easy to stimulate nerve excitation, but also easy to induce the occurrence of urinary tract infections, should also try to avoid; 4, to avoid fatigue, anxiety, to maintain a pleasant mood, life and work should be regular, and moderate, regular exercise, enhance their own immunity. V. Personal perception UTI syndrome is very common in middle-aged and elderly female patients, and the main symptoms are very similar to common cystitis, but because the white blood cells in the urine routine are not high, and most of the clinical examination is negative, so you can not use the treatment of general infections to treat urethral syndrome. At the same time, because the cause of most urethral syndromes is unknown, can not be eradicated, easy to recur, so the clinical treatment for patients with the same patients as this case mainly for symptomatic relief, psychological counseling, strengthening exercise, especially psychological counseling is the most important, the patient’s subjective anxiety will exacerbate the symptoms, and the symptoms aggravate the anxiety, which led to the eventual emergence of some patients with anxiety depression, the lives of patients and families are affected. Patients with urethral syndrome should not only be treated for physical illness, but also for mental illness.