An occupying lesion is an ultrasound, CT or MRI that reveals a nodule in the liver, a nodule that is often referred to as a growth in the liver. It can be either benign or malignant. Benign occupying lesions usually have no conscious symptoms, grow slowly and are not harmful to the body, and are mostly found during physical examinations. Malignant occupying lesions are mainly primary and secondary hepatocellular carcinoma, which develop more rapidly and damage the liver more severely, and can endanger a person’s life. When an occupying lesion is found, it needs to be further examined, including tumor markers, and enhanced MRI and enhanced CT to distinguish whether it is benign or malignant. Malignant lesions need to be promptly treated in oncology hospitals, whether interventional treatment, or use of ablation, radiotherapy, or hepatectomy, depending on the location of the lesion.