Left distal femoral epiphysis seems to see low-density shadow generally refers to the X-ray local low-density tissue, need to be treated according to the cause of the disease, generally avoid excessive exercise and other general treatment, anti-tumor or anti-tuberculosis and other medications, and if necessary, surgical treatment. 1. Bone cysts: for cystic lesions in the bone caused by the distal metaphysis of the left femur seems to see low density shadow. Slight bone cysts can be treated conservatively and excessive exercise can be avoided. Severe bone cysts or pathological fractures can be treated with surgery. 2. Bone tuberculosis: Mycobacterium tuberculosis invades the bones and causes localized bone tuberculosis, and low-density shadow appears in the distal metaphysis of the left femur. For treatment, regular, whole course and sufficient amount of anti-tuberculosis treatment should be carried out, and local lesion resection should be performed if necessary. 3. Osteofibrous anomalous proliferative disease: it is a benign osteofibrous tissue disease, in which normal bone tissue is replaced by osteoblastic osteofibrous tissue. Conservative treatment can be given when it progresses slowly, and surgical radical resection is recommended when it progresses faster or causes local pain. 4. Bone tumors: such as osteochondroma, osteosarcoma and other diseases in the early stage of the disease, the patient in the X-ray film can appear in the left distal femoral epiphysis seems to see low-density shadow. It is recommended to carry out puncture biopsy to clarify the pathology, and then perform further surgery, chemotherapy and other treatments. It is recommended to consult a doctor in time to identify the cause of the disease and carry out targeted treatment with the help of the doctor.